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Inadequate ripening of the cervix is associated with failure of induction or prolonged labor. The current approach to evaluate the state of the cervix relies on digital examination and sonographic examination. Romero, “Effect of depth on shear-wave elastography estimated in the internal and external cervical os during pregnancy,” J. Romero, “Evaluation of cervical stiffness during pregnancy using semiquantitative ultrasound elastography,” Ultrasound Obst. Herein, we present a novel imaging method that combines ultrasound (US) and photoacoustic (PA) techniques to evaluate cervical remodeling by assessing the relative collagen and water content of this organ. The method was tested in vitro in extracted collagen phantoms and ex vivo in murine cervical tissues that were collected in mid-pregnancy and at term. If your lookin' for love, this is probably not the group for you.

Mahendroo, “Distinct reorganization of collagen architecture in lipopolysaccharide-mediated premature cervical remodeling,” Biol. Stipic, “The value of ultrasound measurement of cervical length and parity in prediction of cesarean section risk in term premature rupture of membranes and unfavorable cervix,” J.